Moderna to Launch Clinical Trials of Its mRNA Vaccine for HIV

Moderna, a US-based pharmaceutical company, is set to launch phase-I clinical trials of the world’s first mRNA-based vaccine for HIV.

According to details, Moderna has enrolled 56 healthy adults without HIV to test the safety and basic immune response of the HIV vaccine.


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Speaking to the media, CEO Moderna, Stephane Bancel, said, “the success of our mRNA-based Coronavirus vaccine encouraged us to pursue the development of mRNA-based HIV vaccine.”

Moderna has developed the HIV vaccine in collaboration with the International AIDS Vaccine Initiative (IAVI) and the Bill and Melinda Gates Foundation (BMGF).


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Named mRNA-1644, Moderna’s HIV vaccine is based on the same mRNA platform as its highly effective COVID-19 vaccine. Moderna and Pfizer, both US-based companies, are the only two vaccine manufacturers who have developed mRNA-based COVID-19 vaccines.

Besides mRNA-1644, Moderna will also launch the clinical trials of another version of the HIV vaccine called mRNA-1644v2-Core.